Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9453.002 | 0.9674 | 0.9483 | 1.2655 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9453.002 | 0.9641 | 0.9430 | 1.2655 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9453.002 | 0.9446 | 0.9119 | 1.2655 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9453.002 | 0.3851 | -0.0591 | 1.2655 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 9453.002 | 0.2213 | -0.3927 | 1.2655 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 9453.002 | 0.1690 | -0.5092 | 1.2655 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 9453.002 | 0.1842 | -0.4746 | 1.2655 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 9453.002 | 0.1981 | -0.4437 | 1.2655 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 9453.002 | 0.2180 | -0.3999 | 1.2655 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9469.002 | 1.0703 | 1.1214 | 1.1541 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9469.002 | 0.9466 | 0.9071 | 1.1541 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9469.002 | 1.0006 | 1.0011 | 1.1541 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9469.002 | 0.5881 | 0.2626 | 1.1541 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.016 | uM | 9469.002 | 0.3597 | -0.1754 | 1.1541 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.08 | uM | 9469.002 | 0.2228 | -0.4555 | 1.1541 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 0.4 | uM | 9469.002 | 0.2242 | -0.4524 | 1.1541 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 2 | uM | 9469.002 | 0.2117 | -0.4790 | 1.1541 | |
| HCC38 | TNBC | Basal B | Docetaxel | TUBB | TUBB | 10 | uM | 9469.002 | 0.3047 | -0.2859 | 1.1541 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7857.002 | 1.0247 | 1.0413 | 1.1921 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7857.002 | 0.9806 | 0.9675 | 1.1921 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7857.002 | 0.9721 | 0.9531 | 1.1921 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7857.002 | 0.8700 | 0.7795 | 1.1921 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7857.002 | 0.4871 | 0.0939 | 1.1921 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7857.002 | 0.2344 | -0.4077 | 1.1921 | |
| HCC70 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7857.002 | 0.2442 | -0.3871 | 1.1921 |