Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9421.002 | 1.0098 | 1.0371 | 0.5336 | |
HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9421.002 | 0.8254 | 0.3958 | 0.5336 | |
HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9421.002 | 0.5801 | -0.2791 | 0.5336 | |
HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9421.002 | 0.5558 | -0.3346 | 0.5336 | |
HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9421.002 | 0.5816 | -0.2756 | 0.5336 | |
HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9421.002 | 0.6528 | -0.1006 | 0.5336 | |
HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9421.002 | 0.6535 | -0.0989 | 0.5336 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7853.002 | 0.9752 | 0.9829 | 2.9249 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7853.002 | 1.0452 | 1.0305 | 2.9249 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7853.002 | 0.9809 | 0.9868 | 2.9249 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7853.002 | 0.9323 | 0.9526 | 2.9249 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7853.002 | 0.8160 | 0.8657 | 2.9249 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7853.002 | 0.6617 | 0.7367 | 2.9249 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7853.002 | 0.5904 | 0.6702 | 2.9249 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7853.002 | 0.6666 | 0.7411 | 2.9249 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7853.002 | 0.6901 | 0.7618 | 2.9249 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10056.002 | 1.0250 | 1.0574 | 0.8731 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10056.002 | 1.0273 | 1.0628 | 0.8731 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10056.002 | 1.0131 | 1.0300 | 0.8731 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10056.002 | 0.9379 | 0.8585 | 0.8731 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 10056.002 | 0.6571 | 0.2363 | 0.8731 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 10056.002 | 0.3933 | -0.3132 | 0.8731 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 10056.002 | 0.3082 | -0.4805 | 0.8731 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 10056.002 | 0.3367 | -0.4252 | 0.8731 | |
HCC3153 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 10056.002 | 0.3756 | -0.3486 | 0.8731 |