Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 7848.002 | 0.6625 | -0.0426 | 0.5588 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 7848.002 | 0.6039 | -0.1890 | 0.5588 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 7848.002 | 0.6305 | -0.1238 | 0.5588 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 7848.002 | 0.6665 | -0.0325 | 0.5588 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 7848.002 | 0.6885 | 0.0255 | 0.5588 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7849.002 | 1.0115 | 1.0417 | 0.5525 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7849.002 | 1.0716 | 1.2665 | 0.5525 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7849.002 | 0.9731 | 0.9037 | 0.5525 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7849.002 | 0.8687 | 0.5503 | 0.5525 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 7849.002 | 0.7098 | 0.0754 | 0.5525 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 7849.002 | 0.6778 | -0.0108 | 0.5525 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 7849.002 | 0.6168 | -0.1658 | 0.5525 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 7849.002 | 0.7240 | 0.1146 | 0.5525 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 7849.002 | 0.7083 | 0.0715 | 0.5525 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9420.002 | 0.9957 | 0.9734 | 0.3242 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9420.002 | 1.1001 | 1.6841 | 0.3242 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9420.002 | 0.9738 | 0.8426 | 0.3242 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9420.002 | 0.8670 | 0.2878 | 0.3242 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9420.002 | 0.6549 | -0.4581 | 0.3242 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9420.002 | 0.6440 | -0.4854 | 0.3242 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9420.002 | 0.6813 | -0.3879 | 0.3242 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9420.002 | 0.6891 | -0.3658 | 0.3242 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9420.002 | 0.6798 | -0.3921 | 0.3242 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9421.002 | 1.0137 | 1.0518 | 0.5336 | |
| HCC2185 | TNBC | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9421.002 | 0.9778 | 0.9175 | 0.5336 |