Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7876.002 | 1.0124 | 1.0224 | 1.1036 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7876.002 | 0.8465 | 0.7197 | 1.1036 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 7876.002 | 0.4808 | 0.0301 | 1.1036 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 7876.002 | 0.3470 | -0.2335 | 1.1036 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 7876.002 | 0.3438 | -0.2400 | 1.1036 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 7876.002 | 0.3671 | -0.1934 | 1.1036 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 7876.002 | 0.3602 | -0.2072 | 1.1036 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10077.002 | 1.0128 | 1.0594 | 0.4343 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10077.002 | 1.1216 | 1.6051 | 0.4343 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10077.002 | 0.9805 | 0.9115 | 0.4343 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10077.002 | 1.0115 | 1.0535 | 0.4343 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 10077.002 | 0.9546 | 0.7970 | 0.4343 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 10077.002 | 0.8158 | 0.2517 | 0.4343 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 10077.002 | 0.8092 | 0.2282 | 0.4343 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 10077.002 | 0.8531 | 0.3874 | 0.4343 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 10077.002 | 0.7427 | 0.0081 | 0.4343 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10265.002 | 0.9399 | 0.6635 | 0.3365 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10265.002 | 1.1272 | 1.8548 | 0.3365 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10265.002 | 0.9422 | 0.6755 | 0.3365 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10265.002 | 0.9479 | 0.7061 | 0.3365 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 10265.002 | 0.9153 | 0.5373 | 0.3365 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 10265.002 | 0.7599 | -0.1155 | 0.3365 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 10265.002 | 0.7211 | -0.2432 | 0.3365 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 10265.002 | 0.8003 | 0.0315 | 0.3365 | |
| MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 10265.002 | 0.7078 | -0.2837 | 0.3365 |