Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-157	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.0000256	uM	10093.002	1.0645	1.1392	0.9296
MDA-MB-157	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.000128	uM	10093.002	1.0259	1.0558	0.9296
MDA-MB-157	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.00064	uM	10093.002	1.0172	1.0371	0.9296
MDA-MB-157	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.0032	uM	10093.002	0.4014	-0.2509	0.9296
MDA-MB-157	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.016	uM	10093.002	0.2209	-0.6059	0.9296
MDA-MB-157	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.08	uM	10093.002	0.1545	-0.7318	0.9296
MDA-MB-157	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.4	uM	10093.002	0.1223	-0.7913	0.9296
MDA-MB-157	TNBC	Basal B	Docetaxel	TUBB	TUBB	2	uM	10093.002	0.1416	-0.7557	0.9296
MDA-MB-157	TNBC	Basal B	Docetaxel	TUBB	TUBB	10	uM	10093.002	0.1245	-0.7874	0.9296
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	7885.002	0.9845	0.9565	0.7110
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	7885.002	0.9194	0.7771	0.7110
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	7885.002	0.9546	0.8735	0.7110
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	7885.002	1.0164	1.0464	0.7110
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	7885.002	0.8037	0.4707	0.7110
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.08	uM	7885.002	0.7719	0.3896	0.7110
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.4	uM	7885.002	0.7487	0.3312	0.7110
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	2	uM	7885.002	0.7616	0.3635	0.7110
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	10	uM	7885.002	0.8012	0.4642	0.7110
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	7886.002	1.0150	1.0420	0.7173
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	7886.002	1.0216	1.0605	0.7173
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	7886.002	1.0138	1.0386	0.7173
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	7886.002	0.9255	0.7954	0.7173
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	7886.002	0.8093	0.4891	0.7173
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.08	uM	7886.002	0.7526	0.3458	0.7173
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	0.4	uM	7886.002	0.7337	0.2987	0.7173

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)