Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	2	uM	7886.002	0.7685	0.3856	0.7173
MDA-MB-175-VII	HR+	Luminal	Docetaxel	TUBB	TUBB	10	uM	7886.002	0.7674	0.3827	0.7173
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.0000256	uM	7892.002	0.9701	0.9751	2.4193
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.000128	uM	7892.002	1.0430	1.0351	2.4193
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.00064	uM	7892.002	0.9840	0.9867	2.4193
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.0032	uM	7892.002	0.8075	0.8308	2.4193
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.016	uM	7892.002	0.4488	0.4362	2.4193
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.08	uM	7892.002	0.2221	0.0737	2.4193
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.4	uM	7892.002	0.2240	0.0775	2.4193
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	2	uM	7892.002	0.2306	0.0907	2.4193
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	10	uM	7892.002	0.2865	0.1929	2.4193
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.0000256	uM	7893.002	1.0144	1.0122	2.3454
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.000128	uM	7893.002	0.9211	0.9311	2.3454
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.00064	uM	7893.002	0.9129	0.9238	2.3454
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.0032	uM	7893.002	0.7409	0.7600	2.3454
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.016	uM	7893.002	0.3900	0.3387	2.3454
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.08	uM	7893.002	0.2620	0.1297	2.3454
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.4	uM	7893.002	0.2419	0.0920	2.3454
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	2	uM	7893.002	0.2727	0.1492	2.3454
MDA-MB-231	TNBC	Basal B	Docetaxel	TUBB	TUBB	10	uM	7893.002	0.2892	0.1784	2.3454
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	7896.002	1.0491	1.0855	1.1441
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	7896.002	1.0811	1.1411	1.1441
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	7896.002	0.9955	0.9921	1.1441
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	7896.002	0.9839	0.9718	1.1441
MDA-MB-361	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	7896.002	0.6301	0.3357	1.1441

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)