Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 7875.002 | 0.5495 | 0.4409 | 1.8262 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 7875.002 | 0.3977 | 0.2072 | 1.8262 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 7875.002 | 0.3538 | 0.1323 | 1.8262 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 7875.002 | 0.3630 | 0.1482 | 1.8262 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 7875.002 | 0.3915 | 0.1968 | 1.8262 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9583.002 | 0.9552 | 0.9286 | 1.2590 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9583.002 | 1.0238 | 1.0377 | 1.2590 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9583.002 | 1.0166 | 1.0263 | 1.2590 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9583.002 | 0.8396 | 0.7407 | 1.2590 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9583.002 | 0.6834 | 0.4781 | 1.2590 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9583.002 | 0.4768 | 0.1105 | 1.2590 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9583.002 | 0.4802 | 0.1168 | 1.2590 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9583.002 | 0.4899 | 0.1347 | 1.2590 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9583.002 | 0.5065 | 0.1652 | 1.2590 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10073.002 | 1.0150 | 1.0386 | 0.7762 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10073.002 | 0.9871 | 0.9668 | 0.7762 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10073.002 | 1.0038 | 1.0097 | 0.7762 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10073.002 | 0.9243 | 0.8072 | 0.7762 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 10073.002 | 0.8263 | 0.5642 | 0.7762 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 10073.002 | 0.7031 | 0.2705 | 0.7762 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 10073.002 | 0.6474 | 0.1423 | 0.7762 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 10073.002 | 0.6692 | 0.1921 | 0.7762 | |
MCF7 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 10073.002 | 0.6951 | 0.2519 | 0.7762 | |
MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7876.002 | 0.9588 | 0.9251 | 1.1036 | |
MDA-MB-134-VI | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7876.002 | 1.0050 | 1.0091 | 1.1036 |