Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.016
uM
7875.002
0.5495 0.4409 1.8262
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.08
uM
7875.002
0.3977 0.2072 1.8262
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.4
uM
7875.002
0.3538 0.1323 1.8262
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
2
uM
7875.002
0.3630 0.1482 1.8262
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
10
uM
7875.002
0.3915 0.1968 1.8262
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.0000256
uM
9583.002
0.9552 0.9286 1.2590
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.000128
uM
9583.002
1.0238 1.0377 1.2590
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.00064
uM
9583.002
1.0166 1.0263 1.2590
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.0032
uM
9583.002
0.8396 0.7407 1.2590
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.016
uM
9583.002
0.6834 0.4781 1.2590
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.08
uM
9583.002
0.4768 0.1105 1.2590
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.4
uM
9583.002
0.4802 0.1168 1.2590
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
2
uM
9583.002
0.4899 0.1347 1.2590
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
10
uM
9583.002
0.5065 0.1652 1.2590
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.0000256
uM
10073.002
1.0150 1.0386 0.7762
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.000128
uM
10073.002
0.9871 0.9668 0.7762
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.00064
uM
10073.002
1.0038 1.0097 0.7762
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.0032
uM
10073.002
0.9243 0.8072 0.7762
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.016
uM
10073.002
0.8263 0.5642 0.7762
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.08
uM
10073.002
0.7031 0.2705 0.7762
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
0.4
uM
10073.002
0.6474 0.1423 0.7762
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
2
uM
10073.002
0.6692 0.1921 0.7762
MCF7
HR+
Luminal
Docetaxel
TUBB
TUBB
10
uM
10073.002
0.6951 0.2519 0.7762
MDA-MB-134-VI
HR+
Luminal
Docetaxel
TUBB
TUBB
0.0000256
uM
7876.002
0.9588 0.9251 1.1036
MDA-MB-134-VI
HR+
Luminal
Docetaxel
TUBB
TUBB
0.000128
uM
7876.002
1.0050 1.0091 1.1036