Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 12622.176 | 1.0188 | 1.0149 | 2.5005 | |
| LY2 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12627.176 | 0.9861 | 0.9771 | 1.2157 | |
| LY2 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12627.176 | 0.9965 | 0.9943 | 1.2157 | |
| LY2 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12627.176 | 1.0034 | 1.0056 | 1.2157 | |
| LY2 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12627.176 | 1.0121 | 1.0200 | 1.2157 | |
| LY2 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12627.176 | 1.0167 | 1.0275 | 1.2157 | |
| LY2 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12627.176 | 1.0185 | 1.0303 | 1.2157 | |
| LY2 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12627.176 | 0.9932 | 0.9887 | 1.2157 | |
| LY2 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12627.176 | 0.9802 | 0.9673 | 1.2157 | |
| LY2 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12627.176 | 0.9652 | 0.9425 | 1.2157 | |
| MCF 10A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12944.176 | 0.9887 | 0.9912 | 2.5862 | |
| MCF 10A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12944.176 | 1.0346 | 1.0265 | 2.5862 | |
| MCF 10A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12944.176 | 0.9774 | 0.9824 | 2.5862 | |
| MCF 10A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12944.176 | 0.9747 | 0.9803 | 2.5862 | |
| MCF 10A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12944.176 | 0.9332 | 0.9472 | 2.5862 | |
| MCF 10A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12944.176 | 0.9031 | 0.9227 | 2.5862 | |
| MCF 10A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 12944.176 | 0.9398 | 0.9526 | 2.5862 | |
| MCF 10A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 12944.176 | 0.9477 | 0.9589 | 2.5862 | |
| MCF 10A | NM | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 12944.176 | 0.8841 | 0.9070 | 2.5862 | |
| MCF 10F | NM | - | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13750.176 | 0.9696 | 0.9602 | 1.5387 | |
| MCF 10F | NM | - | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13750.176 | 0.9320 | 0.9106 | 1.5387 | |
| MCF 10F | NM | - | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13750.176 | 0.9788 | 0.9723 | 1.5387 | |
| MCF 10F | NM | - | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13750.176 | 0.9710 | 0.9621 | 1.5387 | |
| MCF 10F | NM | - | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13750.176 | 0.9386 | 0.9193 | 1.5387 | |
| MCF 10F | NM | - | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13750.176 | 0.9689 | 0.9594 | 1.5387 |