Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Dichloroacetate | PDK | PDK | 0.133 | uM | 13750.176 | 0.9642 | 0.9532 | 1.5387 | |
| MCF 10F | NM | - | Dichloroacetate | PDK | PDK | 0.667 | uM | 13750.176 | 0.9629 | 0.9515 | 1.5387 | |
| MCF 10F | NM | - | Dichloroacetate | PDK | PDK | 3.33 | uM | 13750.176 | 0.8850 | 0.8474 | 1.5387 | |
| MCF12A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12949.176 | 1.0029 | 1.0035 | 1.6075 | |
| MCF12A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12949.176 | 0.9600 | 0.9499 | 1.6075 | |
| MCF12A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12949.176 | 1.0058 | 1.0073 | 1.6075 | |
| MCF12A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12949.176 | 1.0473 | 1.0583 | 1.6075 | |
| MCF12A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12949.176 | 0.9549 | 0.9434 | 1.6075 | |
| MCF12A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12949.176 | 0.8994 | 0.8723 | 1.6075 | |
| MCF12A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 12949.176 | 0.8592 | 0.8199 | 1.6075 | |
| MCF12A | NM | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 12949.176 | 0.9290 | 0.9105 | 1.6075 | |
| MCF12A | NM | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 12949.176 | 0.8044 | 0.7468 | 1.6075 | |
| MCF7 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12657.176 | 0.9912 | 0.9836 | 1.0711 | |
| MCF7 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12657.176 | 0.9920 | 0.9851 | 1.0711 | |
| MCF7 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12657.176 | 1.0005 | 1.0010 | 1.0711 | |
| MCF7 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12657.176 | 1.0066 | 1.0123 | 1.0711 | |
| MCF7 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12657.176 | 0.9830 | 0.9682 | 1.0711 | |
| MCF7 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12657.176 | 0.9959 | 0.9923 | 1.0711 | |
| MCF7 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12657.176 | 0.9915 | 0.9841 | 1.0711 | |
| MCF7 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12657.176 | 0.9896 | 0.9805 | 1.0711 | |
| MCF7 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12657.176 | 0.9685 | 0.9410 | 1.0711 | |
| MDA-MB-134-VI | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12662.176 | 0.9313 | 0.9231 | 1.8146 | |
| MDA-MB-134-VI | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12662.176 | 0.9366 | 0.9291 | 1.8146 | |
| MDA-MB-134-VI | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12662.176 | 0.9679 | 0.9644 | 1.8146 | |
| MDA-MB-134-VI | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12662.176 | 0.9671 | 0.9635 | 1.8146 |