Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9583.121 | 0.8740 | 0.7624 | 1.0648 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9583.121 | 0.6129 | 0.2629 | 1.0648 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 3.68 | uM | 9583.121 | 0.5584 | 0.1571 | 1.0648 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9583.121 | 0.4792 | 0.0022 | 1.0648 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 92 | uM | 9583.121 | 0.0803 | -0.8128 | 1.0648 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 10073.034 | 1.0068 | 1.0248 | 0.5531 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 10073.034 | 0.9978 | 0.9921 | 0.5531 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 10073.034 | 0.9834 | 0.9403 | 0.5531 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 10073.034 | 0.9913 | 0.9688 | 0.5531 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 10073.034 | 0.9548 | 0.8396 | 0.5531 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 10073.034 | 0.6075 | -0.1878 | 0.5531 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 10073.034 | 0.7614 | 0.2219 | 0.5531 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 10073.034 | 0.7445 | 0.1731 | 0.5531 | |
| MCF7 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 10073.034 | 0.1471 | -0.9375 | 0.5531 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7876.007 | 1.0310 | 1.0605 | 1.0246 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7876.007 | 0.9817 | 0.9642 | 1.0246 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7876.007 | 1.0538 | 1.1049 | 1.0246 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7876.007 | 1.0166 | 1.0323 | 1.0246 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7876.007 | 0.9957 | 0.9916 | 1.0246 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7876.007 | 0.8471 | 0.7010 | 1.0246 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7876.007 | 0.3485 | -0.2851 | 1.0246 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7876.007 | 0.1070 | -0.7742 | 1.0246 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7876.007 | 0.0516 | -0.8892 | 1.0246 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7877.007 | 1.0826 | 1.2841 | 0.5977 | |
| MDA-MB-134-VI | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7877.007 | 0.7731 | 0.3003 | 0.5977 |