Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12979.176 | 0.9668 | 0.9342 | 1.0091 | |
| 21MT-1 | HER2amp | - | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13719.176 | 0.9499 | 0.8850 | 0.8672 | |
| 21MT-1 | HER2amp | - | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13719.176 | 0.9593 | 0.9064 | 0.8672 | |
| 21MT-1 | HER2amp | - | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13719.176 | 0.9612 | 0.9108 | 0.8672 | |
| 21MT-1 | HER2amp | - | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13719.176 | 0.9990 | 0.9976 | 0.8672 | |
| 21MT-1 | HER2amp | - | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13719.176 | 0.9755 | 0.9435 | 0.8672 | |
| 21MT-1 | HER2amp | - | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13719.176 | 0.9671 | 0.9242 | 0.8672 | |
| 21MT-1 | HER2amp | - | Dichloroacetate | PDK | PDK | 0.133 | uM | 13719.176 | 0.9852 | 0.9660 | 0.8672 | |
| 21MT-1 | HER2amp | - | Dichloroacetate | PDK | PDK | 0.667 | uM | 13719.176 | 0.9872 | 0.9706 | 0.8672 | |
| 21MT-1 | HER2amp | - | Dichloroacetate | PDK | PDK | 3.33 | uM | 13719.176 | 0.9667 | 0.9233 | 0.8672 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13575.176 | 0.9938 | 0.9916 | 1.4733 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13575.176 | 0.9759 | 0.9672 | 1.4733 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13575.176 | 1.0629 | 1.0845 | 1.4733 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13575.176 | 1.0120 | 1.0162 | 1.4733 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13575.176 | 0.9585 | 0.9433 | 1.4733 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13575.176 | 0.9572 | 0.9415 | 1.4733 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 0.133 | uM | 13575.176 | 0.9551 | 0.9385 | 1.4733 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 0.667 | uM | 13575.176 | 0.9949 | 0.9930 | 1.4733 | |
| 21NT | HER2amp | - | Dichloroacetate | PDK | PDK | 3.33 | uM | 13575.176 | 0.8546 | 0.7977 | 1.4733 | |
| 600MPE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13091.176 | 0.9377 | 0.8581 | 0.8746 | |
| 600MPE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13091.176 | 0.9938 | 0.9859 | 0.8746 | |
| 600MPE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13091.176 | 0.9889 | 0.9746 | 0.8746 | |
| 600MPE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13091.176 | 0.9804 | 0.9552 | 0.8746 | |
| 600MPE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13091.176 | 0.9734 | 0.9393 | 0.8746 | |
| 600MPE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13091.176 | 0.9505 | 0.8872 | 0.8746 |