Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12617.176 | 1.0164 | 1.0211 | 1.5509 | |
| HCC38 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12617.176 | 0.9824 | 0.9772 | 1.5509 | |
| HCC38 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12617.176 | 0.9856 | 0.9814 | 1.5509 | |
| HCC38 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12617.176 | 0.9714 | 0.9629 | 1.5509 | |
| HCC38 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12617.176 | 0.9740 | 0.9663 | 1.5509 | |
| HCC38 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 12617.176 | 0.9804 | 0.9747 | 1.5509 | |
| HCC38 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 12617.176 | 0.9879 | 0.9844 | 1.5509 | |
| HCC38 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 12617.176 | 0.9510 | 0.9362 | 1.5509 | |
| HCC70 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12714.176 | 0.9563 | 0.7318 | 0.3108 | |
| HCC70 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12714.176 | 0.9494 | 0.6924 | 0.3108 | |
| HCC70 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12714.176 | 0.9807 | 0.8783 | 0.3108 | |
| HCC70 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12714.176 | 1.0030 | 1.0192 | 0.3108 | |
| HCC70 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12714.176 | 0.9648 | 0.7821 | 0.3108 | |
| HCC70 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12714.176 | 0.9649 | 0.7825 | 0.3108 | |
| HCC70 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 12714.176 | 0.9183 | 0.5200 | 0.3108 | |
| HCC70 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 12714.176 | 0.9363 | 0.6184 | 0.3108 | |
| HCC70 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 12714.176 | 0.8646 | 0.2521 | 0.3108 | |
| Hs 578T | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12622.176 | 1.0112 | 1.0089 | 2.5005 | |
| Hs 578T | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12622.176 | 1.0164 | 1.0131 | 2.5005 | |
| Hs 578T | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12622.176 | 1.0447 | 1.0353 | 2.5005 | |
| Hs 578T | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12622.176 | 1.0105 | 1.0084 | 2.5005 | |
| Hs 578T | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12622.176 | 1.0143 | 1.0114 | 2.5005 | |
| Hs 578T | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12622.176 | 0.9998 | 0.9999 | 2.5005 | |
| Hs 578T | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 12622.176 | 1.0080 | 1.0064 | 2.5005 | |
| Hs 578T | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 12622.176 | 0.9934 | 0.9947 | 2.5005 |