Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13135.176 | 0.9968 | 0.9840 | 0.3972 | |
| HCC202 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13135.176 | 0.9825 | 0.9128 | 0.3972 | |
| HCC202 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13135.176 | 0.9584 | 0.7973 | 0.3972 | |
| HCC202 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13135.176 | 0.9790 | 0.8960 | 0.3972 | |
| HCC202 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13135.176 | 0.9484 | 0.7503 | 0.3972 | |
| HCC202 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13135.176 | 0.8842 | 0.4671 | 0.3972 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13583.176 | 0.9551 | 0.8200 | 0.4872 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13583.176 | 1.0507 | 1.2136 | 0.4872 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13583.176 | 1.0066 | 1.0272 | 0.4872 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13583.176 | 1.0300 | 1.1251 | 0.4872 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13583.176 | 1.0073 | 1.0299 | 0.4872 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13583.176 | 0.9528 | 0.8111 | 0.4872 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 13583.176 | 0.9796 | 0.9172 | 0.4872 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 13583.176 | 0.9683 | 0.8720 | 0.4872 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 13583.176 | 0.9225 | 0.6949 | 0.4872 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13733.176 | 0.9406 | 0.8360 | 0.7155 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13733.176 | 0.9745 | 0.9291 | 0.7155 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13733.176 | 0.9729 | 0.9246 | 0.7155 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13733.176 | 0.9865 | 0.9625 | 0.7155 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13733.176 | 0.9850 | 0.9582 | 0.7155 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13733.176 | 0.9639 | 0.8997 | 0.7155 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 13733.176 | 0.9521 | 0.8675 | 0.7155 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 13733.176 | 0.9523 | 0.8680 | 0.7155 | |
| HCC3153 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 13733.176 | 0.9321 | 0.8129 | 0.7155 | |
| HCC38 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12617.176 | 0.9899 | 0.9869 | 1.5509 |