Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12612.176 | 0.9217 | 0.7616 | 0.6422 | |
| HCC1419 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12612.176 | 0.9465 | 0.8358 | 0.6422 | |
| HCC1428 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13107.176 | 0.9505 | 0.8560 | 0.6790 | |
| HCC1428 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13107.176 | 0.9680 | 0.9064 | 0.6790 | |
| HCC1428 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13107.176 | 0.9925 | 0.9779 | 0.6790 | |
| HCC1428 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13107.176 | 0.9419 | 0.8311 | 0.6790 | |
| HCC1428 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13107.176 | 0.9399 | 0.8256 | 0.6790 | |
| HCC1428 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13107.176 | 0.9722 | 0.9186 | 0.6790 | |
| HCC1428 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13107.176 | 0.9230 | 0.7774 | 0.6790 | |
| HCC1428 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13107.176 | 0.9438 | 0.8368 | 0.6790 | |
| HCC1428 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13107.176 | 0.9021 | 0.7183 | 0.6790 | |
| HCC1569 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13038.176 | 0.9782 | 0.9665 | 1.3069 | |
| HCC1569 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13038.176 | 0.9926 | 0.9887 | 1.3069 | |
| HCC1569 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13038.176 | 0.9757 | 0.9627 | 1.3069 | |
| HCC1569 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13038.176 | 0.9525 | 0.9269 | 1.3069 | |
| HCC1569 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13038.176 | 0.9780 | 0.9662 | 1.3069 | |
| HCC1569 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13038.176 | 0.9543 | 0.9297 | 1.3069 | |
| HCC1569 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 13038.176 | 0.9829 | 0.9737 | 1.3069 | |
| HCC1569 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 13038.176 | 0.9738 | 0.9597 | 1.3069 | |
| HCC1569 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 13038.176 | 0.9534 | 0.9283 | 1.3069 | |
| HCC1806 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12702.176 | 1.0100 | 1.0116 | 1.7142 | |
| HCC1806 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12702.176 | 0.9873 | 0.9851 | 1.7142 | |
| HCC1806 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12702.176 | 0.9731 | 0.9684 | 1.7142 | |
| HCC1806 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12702.176 | 0.9922 | 0.9909 | 1.7142 | |
| HCC1806 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12702.176 | 1.0051 | 1.0059 | 1.7142 |