Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13726.176 | 0.9139 | 0.6031 | 0.4071 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13726.176 | 0.9050 | 0.5649 | 0.4071 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13726.176 | 0.9520 | 0.7724 | 0.4071 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13726.176 | 0.9363 | 0.7013 | 0.4071 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13726.176 | 0.9168 | 0.6155 | 0.4071 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13726.176 | 0.8873 | 0.4909 | 0.4071 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 13726.176 | 0.9387 | 0.7123 | 0.4071 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 13726.176 | 0.9333 | 0.6882 | 0.4071 | |
| HCC1187 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 13726.176 | 0.9312 | 0.6786 | 0.4071 | |
| HCC1395 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13538.176 | 0.9668 | 0.8574 | 0.4572 | |
| HCC1395 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13538.176 | 0.9789 | 0.9087 | 0.4572 | |
| HCC1395 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13538.176 | 0.9671 | 0.8588 | 0.4572 | |
| HCC1395 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13538.176 | 0.9726 | 0.8821 | 0.4572 | |
| HCC1395 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13538.176 | 0.9850 | 0.9349 | 0.4572 | |
| HCC1395 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13538.176 | 0.9483 | 0.7809 | 0.4572 | |
| HCC1395 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 13538.176 | 0.9574 | 0.8183 | 0.4572 | |
| HCC1395 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 13538.176 | 0.9618 | 0.8365 | 0.4572 | |
| HCC1395 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 13538.176 | 0.9540 | 0.8042 | 0.4572 | |
| HCC1419 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12612.176 | 0.9145 | 0.7401 | 0.6422 | |
| HCC1419 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12612.176 | 0.8855 | 0.6550 | 0.6422 | |
| HCC1419 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12612.176 | 0.9227 | 0.7645 | 0.6422 | |
| HCC1419 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12612.176 | 0.9317 | 0.7915 | 0.6422 | |
| HCC1419 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12612.176 | 0.9035 | 0.7078 | 0.6422 | |
| HCC1419 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12612.176 | 0.9544 | 0.8599 | 0.6422 | |
| HCC1419 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12612.176 | 0.9605 | 0.8783 | 0.6422 |