Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7860.043 | 0.0763 | -0.9357 | 0.7488 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7860.043 | 0.0138 | -0.9934 | 0.7488 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9501.121 | 1.0538 | 1.1529 | 0.7121 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9501.121 | 1.0417 | 1.1182 | 0.7121 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9501.121 | 1.0706 | 1.2012 | 0.7121 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9501.121 | 1.0682 | 1.1942 | 0.7121 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9501.121 | 0.8918 | 0.7028 | 0.7121 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9501.121 | 0.5329 | -0.1737 | 0.7121 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 3.68 | uM | 9501.121 | 0.0096 | -0.9971 | 0.7121 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9501.121 | 0.0094 | -0.9972 | 0.7121 | |
| HCC70 | TNBC | Basal A | Doxorubicin | TOP2 | TOP | 92 | uM | 9501.121 | 0.0021 | -0.9997 | 0.7121 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7911.007 | 1.0740 | 1.0939 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7911.007 | 1.0467 | 1.0596 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7911.007 | 1.1354 | 1.1702 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7911.007 | 1.0180 | 1.0231 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7911.007 | 1.0583 | 1.0742 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7911.007 | 0.8936 | 0.8604 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7911.007 | 0.7378 | 0.6448 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7911.007 | 0.0671 | -0.6482 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7911.007 | 0.1173 | -0.4958 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 10124.034 | 1.4272 | 1.3410 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 10124.034 | 1.0212 | 1.0187 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 10124.034 | 1.2219 | 1.1855 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 10124.034 | 0.9568 | 0.9613 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.138 | uM | 10124.034 | 0.7214 | 0.7309 | 2.2594 |