Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.69 | uM | 10124.034 | 0.1446 | -0.1501 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 3.45 | uM | 10124.034 | 0.1807 | -0.0621 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 17.2 | uM | 10124.034 | 0.0813 | -0.3414 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 86.2 | uM | 10124.034 | 0.0040 | -0.8261 | 2.2594 | |
| HMT-3522 T4-2 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 10147.034 | 1.1525 | 1.1247 | 2.3470 | |
| HMT-3522 T4-2 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 10147.034 | 1.1923 | 1.1556 | 2.3470 | |
| HMT-3522 T4-2 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 10147.034 | 1.0620 | 1.0519 | 2.3470 | |
| HMT-3522 T4-2 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 10147.034 | 0.8699 | 0.8847 | 2.3470 | |
| HMT-3522 T4-2 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.138 | uM | 10147.034 | 0.5661 | 0.5695 | 2.3470 | |
| HMT-3522 T4-2 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 0.69 | uM | 10147.034 | 0.1642 | -0.0738 | 2.3470 | |
| HMT-3522 T4-2 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 3.45 | uM | 10147.034 | 0.0080 | -0.7445 | 2.3470 | |
| HMT-3522 T4-2 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 17.2 | uM | 10147.034 | 0.0069 | -0.7602 | 2.3470 | |
| HMT-3522 T4-2 | Unknown | Unknown | Doxorubicin | TOP2 | TOP | 86.2 | uM | 10147.034 | 0.0012 | -0.8841 | 2.3470 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7863.007 | 1.1271 | 1.1710 | 1.4578 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7863.007 | 1.0257 | 1.0351 | 1.4578 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7863.007 | 1.0558 | 1.0759 | 1.4578 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7863.007 | 1.0224 | 1.0307 | 1.4578 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7863.007 | 1.0563 | 1.0765 | 1.4578 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7863.007 | 0.7864 | 0.6961 | 1.4578 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7863.007 | 0.6680 | 0.5164 | 1.4578 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7863.007 | 0.1009 | -0.5852 | 1.4578 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7863.007 | 0.1096 | -0.5612 | 1.4578 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 9511.034 | 1.0378 | 1.0675 | 1.1177 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 9511.034 | 1.0339 | 1.0606 | 1.1177 | |
| Hs 578T | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 9511.034 | 1.0391 | 1.0699 | 1.1177 |