Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12702.176 | 1.0004 | 1.0005 | 1.7142 | |
| HCC1806 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 12702.176 | 1.0080 | 1.0093 | 1.7142 | |
| HCC1806 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 12702.176 | 0.9898 | 0.9881 | 1.7142 | |
| HCC1806 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 12702.176 | 0.9238 | 0.9096 | 1.7142 | |
| HCC1937 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13115.176 | 1.0138 | 1.0337 | 0.8197 | |
| HCC1937 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13115.176 | 1.0882 | 1.2172 | 0.8197 | |
| HCC1937 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13115.176 | 1.0386 | 1.0946 | 0.8197 | |
| HCC1937 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13115.176 | 1.0159 | 1.0390 | 0.8197 | |
| HCC1937 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13115.176 | 0.9795 | 0.9501 | 0.8197 | |
| HCC1937 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13115.176 | 1.0046 | 1.0111 | 0.8197 | |
| HCC1937 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 13115.176 | 0.9973 | 0.9935 | 0.8197 | |
| HCC1937 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 13115.176 | 0.9260 | 0.8209 | 0.8197 | |
| HCC1937 | TNBC | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 13115.176 | 0.9699 | 0.9268 | 0.8197 | |
| HCC1954 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13546.176 | 1.0114 | 1.0203 | 1.1206 | |
| HCC1954 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13546.176 | 0.9479 | 0.9067 | 1.1206 | |
| HCC1954 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13546.176 | 1.0122 | 1.0217 | 1.1206 | |
| HCC1954 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13546.176 | 0.9986 | 0.9976 | 1.1206 | |
| HCC1954 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13546.176 | 0.9310 | 0.8765 | 1.1206 | |
| HCC1954 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13546.176 | 0.8781 | 0.7809 | 1.1206 | |
| HCC1954 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.133 | uM | 13546.176 | 0.8933 | 0.8084 | 1.1206 | |
| HCC1954 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 0.667 | uM | 13546.176 | 1.0006 | 1.0011 | 1.1206 | |
| HCC1954 | HER2amp | Basal A | Dichloroacetate | PDK | PDK | 3.33 | uM | 13546.176 | 0.9204 | 0.8572 | 1.1206 | |
| HCC202 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13135.176 | 0.9870 | 0.9354 | 0.3972 | |
| HCC202 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13135.176 | 0.9654 | 0.8301 | 0.3972 | |
| HCC202 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13135.176 | 0.9731 | 0.8674 | 0.3972 |