Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 3.41 | uM | 7529.078 | 0.7512 | 0.3738 | 0.7619 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 17.1 | uM | 7529.078 | 0.5496 | -0.0884 | 0.7619 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 85.2 | uM | 7529.078 | 0.3362 | -0.5216 | 0.7619 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000189 | uM | 10139.034 | 1.0246 | 1.0589 | 0.8381 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000945 | uM | 10139.034 | 1.0063 | 1.0151 | 0.8381 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00472 | uM | 10139.034 | 0.9979 | 0.9951 | 0.8381 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.0236 | uM | 10139.034 | 1.0327 | 1.0782 | 0.8381 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.118 | uM | 10139.034 | 1.0270 | 1.0647 | 0.8381 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.59 | uM | 10139.034 | 0.9567 | 0.8970 | 0.8381 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 2.95 | uM | 10139.034 | 0.8637 | 0.6792 | 0.8381 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 14.8 | uM | 10139.034 | 0.6839 | 0.2711 | 0.8381 | |
| SUM1315MO2 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 73.8 | uM | 10139.034 | 0.3681 | -0.3930 | 0.8381 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000189 | uM | 7918.007 | 0.8988 | 0.9296 | 2.9756 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000945 | uM | 7918.007 | 1.1746 | 1.1111 | 2.9756 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7918.007 | 1.0700 | 1.0460 | 2.9756 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7918.007 | 0.9946 | 0.9964 | 2.9756 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.118 | uM | 7918.007 | 1.1814 | 1.1152 | 2.9756 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.59 | uM | 7918.007 | 0.9498 | 0.9657 | 2.9756 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 2.95 | uM | 7918.007 | 0.7015 | 0.7753 | 2.9756 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 14.8 | uM | 7918.007 | 0.0992 | -0.0801 | 2.9756 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 73.8 | uM | 7918.007 | 0.0242 | -0.4277 | 2.9756 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000189 | uM | 7919.043 | 1.0498 | 1.0309 | 3.1744 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000945 | uM | 7919.043 | 1.0567 | 1.0350 | 3.1744 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7919.043 | 0.9983 | 0.9989 | 3.1744 | |
| SUM159PT | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7919.043 | 0.9868 | 0.9916 | 3.1744 |