Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000189 | uM | 10095.034 | 1.0587 | 1.1502 | 0.7874 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000945 | uM | 10095.034 | 1.0849 | 1.2180 | 0.7874 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00472 | uM | 10095.034 | 1.0207 | 1.0528 | 0.7874 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0236 | uM | 10095.034 | 1.0403 | 1.1030 | 0.7874 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.118 | uM | 10095.034 | 0.9761 | 0.9395 | 0.7874 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.59 | uM | 10095.034 | 1.0599 | 1.1533 | 0.7874 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 2.95 | uM | 10095.034 | 0.7752 | 0.4473 | 0.7874 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 14.8 | uM | 10095.034 | 0.6286 | 0.1091 | 0.7874 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 73.8 | uM | 10095.034 | 0.5678 | -0.0254 | 0.7874 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000189 | uM | 7897.007 | 0.9520 | 0.8910 | 0.8772 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000945 | uM | 7897.007 | 0.9083 | 0.7923 | 0.8772 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7897.007 | 0.9476 | 0.8810 | 0.8772 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7897.007 | 0.9972 | 0.9936 | 0.8772 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.118 | uM | 7897.007 | 0.9762 | 0.9457 | 0.8772 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.59 | uM | 7897.007 | 0.9458 | 0.8770 | 0.8772 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 2.95 | uM | 7897.007 | 0.9637 | 0.9173 | 0.8772 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 14.8 | uM | 7897.007 | 0.6103 | 0.1390 | 0.8772 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 73.8 | uM | 7897.007 | 0.1272 | -0.8093 | 0.8772 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9664.121 | 1.0343 | 1.0948 | 0.7294 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9664.121 | 1.0716 | 1.1989 | 0.7294 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9664.121 | 1.0036 | 1.0098 | 0.7294 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9664.121 | 1.0715 | 1.1986 | 0.7294 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9664.121 | 1.0456 | 1.1260 | 0.7294 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9664.121 | 1.0563 | 1.1559 | 0.7294 | |
| MDA-MB-415 | HR+ | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9664.121 | 0.9393 | 0.8355 | 0.7294 |