Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7896.007 | 1.0428 | 1.0762 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7896.007 | 1.0088 | 1.0157 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.118 | uM | 7896.007 | 0.9939 | 0.9891 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.59 | uM | 7896.007 | 0.9902 | 0.9824 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 2.95 | uM | 7896.007 | 0.8968 | 0.8146 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 14.8 | uM | 7896.007 | 0.6671 | 0.3935 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 73.8 | uM | 7896.007 | 0.4929 | 0.0635 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000189 | uM | 7896.043 | 0.9829 | 0.9602 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000945 | uM | 7896.043 | 0.9530 | 0.8906 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7896.043 | 0.9582 | 0.9027 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7896.043 | 0.9851 | 0.9651 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.118 | uM | 7896.043 | 0.9934 | 0.9846 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.59 | uM | 7896.043 | 0.9619 | 0.9113 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 2.95 | uM | 7896.043 | 0.9839 | 0.9623 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 14.8 | uM | 7896.043 | 0.9921 | 0.9816 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 73.8 | uM | 7896.043 | 0.8724 | 0.7049 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9648.121 | 1.0657 | 1.2043 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9648.121 | 0.9905 | 0.9711 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9648.121 | 1.0300 | 1.0924 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9648.121 | 1.0212 | 1.0651 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9648.121 | 1.0020 | 1.0061 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9648.121 | 1.0377 | 1.1166 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9648.121 | 0.6995 | 0.1577 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 9648.121 | 0.5418 | -0.2169 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 9648.121 | 0.5102 | -0.2857 | 0.6537 |