Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.136 | uM | 9501.121 | 1.0899 | 1.2570 | 0.7121 | |
| HCC70 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.682 | uM | 9501.121 | 1.0860 | 1.2456 | 0.7121 | |
| HCC70 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 3.41 | uM | 9501.121 | 0.9949 | 0.9857 | 0.7121 | |
| HCC70 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 17.1 | uM | 9501.121 | 0.6386 | 0.0653 | 0.7121 | |
| HCC70 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 85.2 | uM | 9501.121 | 0.0684 | -0.9538 | 0.7121 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.000189 | uM | 7911.007 | 1.0386 | 1.0493 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.000945 | uM | 7911.007 | 1.2015 | 1.2506 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7911.007 | 1.0712 | 1.0904 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7911.007 | 1.0504 | 1.0642 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.118 | uM | 7911.007 | 1.1597 | 1.1999 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.59 | uM | 7911.007 | 1.0903 | 1.1143 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 2.95 | uM | 7911.007 | 0.9691 | 0.9601 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 14.8 | uM | 7911.007 | 1.0326 | 1.0417 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 73.8 | uM | 7911.007 | 0.8554 | 0.8089 | 1.5549 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.000189 | uM | 10124.034 | 1.4484 | 1.3564 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.000945 | uM | 10124.034 | 0.9535 | 0.9583 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.00472 | uM | 10124.034 | 1.0012 | 1.0011 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.0236 | uM | 10124.034 | 1.1931 | 1.1625 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.118 | uM | 10124.034 | 0.9619 | 0.9659 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.59 | uM | 10124.034 | 0.8980 | 0.9070 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 2.95 | uM | 10124.034 | 1.0920 | 1.0795 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 14.8 | uM | 10124.034 | 0.4759 | 0.4397 | 2.2594 | |
| HMT-3522 S1 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 73.8 | uM | 10124.034 | 0.2331 | 0.0497 | 2.2594 | |
| HMT-3522 T4-2 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.000189 | uM | 10147.034 | 1.2140 | 1.1722 | 2.3470 | |
| HMT-3522 T4-2 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.000945 | uM | 10147.034 | 1.1202 | 1.0991 | 2.3470 |