Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 2.95 | uM | 7813.007 | 0.6645 | 0.2267 | 0.8361 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 14.8 | uM | 7813.007 | 0.4693 | -0.1907 | 0.8361 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 73.8 | uM | 7813.007 | 0.1830 | -0.7377 | 0.8361 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000189 | uM | 7816.007 | 0.9487 | 0.9107 | 1.1536 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000945 | uM | 7816.007 | 0.9730 | 0.9532 | 1.1536 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7816.007 | 1.3649 | 1.6190 | 1.1536 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7816.007 | 0.9488 | 0.9109 | 1.1536 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.118 | uM | 7816.007 | 0.9632 | 0.9361 | 1.1536 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.59 | uM | 7816.007 | 0.8708 | 0.7739 | 1.1536 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 2.95 | uM | 7816.007 | 0.8409 | 0.7211 | 1.1536 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 14.8 | uM | 7816.007 | 0.8023 | 0.6524 | 1.1536 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 73.8 | uM | 7816.007 | 0.8335 | 0.7080 | 1.1536 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9254.121 | 0.9917 | 0.9866 | 1.2352 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9254.121 | 0.9693 | 0.9501 | 1.2352 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9254.121 | 1.0311 | 1.0502 | 1.2352 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9254.121 | 1.0171 | 1.0276 | 1.2352 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.136 | uM | 9254.121 | 0.9942 | 0.9907 | 1.2352 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.682 | uM | 9254.121 | 0.8671 | 0.7820 | 1.2352 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 3.41 | uM | 9254.121 | 0.5158 | 0.1702 | 1.2352 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 17.1 | uM | 9254.121 | 0.3662 | -0.1132 | 1.2352 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 85.2 | uM | 9254.121 | 0.0976 | -0.6959 | 1.2352 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9258.121 | 1.0191 | 1.0804 | 0.4800 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9258.121 | 0.9572 | 0.8256 | 0.4800 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9258.121 | 0.9813 | 0.9227 | 0.4800 | |
| HCC1395 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9258.121 | 0.9668 | 0.8642 | 0.4800 |