Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9933.021 | 0.1012 | -0.9980 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00128 | uM | 9953.049 | 1.1454 | 1.5705 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0064 | uM | 9953.049 | 0.8933 | 0.6237 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.032 | uM | 9953.049 | 1.1760 | 1.6985 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.16 | uM | 9953.049 | 0.8319 | 0.4233 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.8 | uM | 9953.049 | 1.0870 | 1.3335 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 4 | uM | 9953.049 | 1.0135 | 1.0502 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 20 | uM | 9953.049 | 1.1568 | 1.6179 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 100 | uM | 9953.049 | 1.1772 | 1.7037 | 0.5411 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 500 | uM | 9953.049 | 1.0461 | 1.1737 | 0.5411 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7931.017 | 1.0913 | 1.1339 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7931.017 | 0.9693 | 0.9543 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7931.017 | 1.0554 | 1.0815 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7931.017 | 0.9731 | 0.9599 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7931.017 | 1.0053 | 1.0078 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7931.017 | 0.8870 | 0.8299 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7931.017 | 0.8236 | 0.7320 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7931.017 | 0.0651 | -0.7361 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7931.017 | 0.0165 | -0.9048 | 1.3488 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7932.017 | 1.0164 | 1.0305 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7932.017 | 0.9627 | 0.9302 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7932.017 | 0.9941 | 0.9891 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7932.017 | 0.9348 | 0.8781 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7932.017 | 0.9759 | 0.9550 | 1.0712 | |
| ZR-75-1 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7932.017 | 0.9330 | 0.8747 | 1.0712 |