Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7906.017 | 1.1764 | 2.0593 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7906.017 | 1.4197 | 4.0035 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7906.017 | 0.9268 | 0.6390 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7906.017 | 1.1998 | 2.2216 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7906.017 | 1.2018 | 2.2355 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7906.017 | 1.0194 | 1.1033 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7906.017 | 0.1144 | -0.9931 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7906.017 | 0.0528 | -0.9991 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7907.017 | 1.1544 | 1.2135 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7907.017 | 0.8809 | 0.8286 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7907.017 | 1.1290 | 1.1789 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7907.017 | 0.9272 | 0.8960 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7907.017 | 1.0643 | 1.0900 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7907.017 | 0.7539 | 0.6382 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7907.017 | 0.5993 | 0.3931 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7907.017 | 0.0540 | -0.7455 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7907.017 | 0.0063 | -0.9443 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7909.13 | 1.1202 | 1.1543 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7909.13 | 0.8600 | 0.8119 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7909.13 | 1.1242 | 1.1594 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7909.13 | 0.9383 | 0.9183 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7909.13 | 1.0281 | 1.0366 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7909.13 | 0.8034 | 0.7328 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7909.13 | 0.6185 | 0.4602 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7909.13 | 0.1024 | -0.5503 | 1.5270 |