Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
ZR75B	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	0.8	uM	9997.049	0.9922	0.9863	1.1423
ZR75B	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	4	uM	9997.049	0.9954	0.9919	1.1423
ZR75B	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	20	uM	9997.049	1.0303	1.0530	1.1423
ZR75B	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	100	uM	9997.049	1.0146	1.0255	1.1423
ZR75B	HR+	Luminal	Cisplatin	DNA cross-linker	DNA cross-linker	500	uM	9997.049	0.9763	0.9585	1.1423
184A1	NM	Basal	CPT-11	TOP1	TOP	0.000218	uM	9047.121	0.9803	0.9505	0.7949
184A1	NM	Basal	CPT-11	TOP1	TOP	0.00109	uM	9047.121	0.9292	0.8235	0.7949
184A1	NM	Basal	CPT-11	TOP1	TOP	0.00546	uM	9047.121	0.9110	0.7787	0.7949
184A1	NM	Basal	CPT-11	TOP1	TOP	0.0273	uM	9047.121	0.9219	0.8056	0.7949
184A1	NM	Basal	CPT-11	TOP1	TOP	0.136	uM	9047.121	0.9391	0.8480	0.7949
184A1	NM	Basal	CPT-11	TOP1	TOP	0.682	uM	9047.121	0.8457	0.6199	0.7949
184A1	NM	Basal	CPT-11	TOP1	TOP	3.41	uM	9047.121	0.8534	0.6383	0.7949
184A1	NM	Basal	CPT-11	TOP1	TOP	17.1	uM	9047.121	0.3387	-0.4877	0.7949
184A1	NM	Basal	CPT-11	TOP1	TOP	85.2	uM	9047.121	0.2391	-0.6694	0.7949
184A1	NM	Basal	CPT-11	TOP1	TOP	0.000189	uM	10002.034	0.9978	0.9934	0.6736
184A1	NM	Basal	CPT-11	TOP1	TOP	0.000945	uM	10002.034	0.9596	0.8812	0.6736
184A1	NM	Basal	CPT-11	TOP1	TOP	0.00472	uM	10002.034	0.9771	0.9324	0.6736
184A1	NM	Basal	CPT-11	TOP1	TOP	0.0236	uM	10002.034	0.9891	0.9677	0.6736
184A1	NM	Basal	CPT-11	TOP1	TOP	0.118	uM	10002.034	0.9996	0.9987	0.6736
184A1	NM	Basal	CPT-11	TOP1	TOP	0.59	uM	10002.034	0.9938	0.9816	0.6736
184A1	NM	Basal	CPT-11	TOP1	TOP	2.95	uM	10002.034	0.9060	0.7273	0.6736
184A1	NM	Basal	CPT-11	TOP1	TOP	14.8	uM	10002.034	0.1090	-0.9255	0.6736
184A1	NM	Basal	CPT-11	TOP1	TOP	73.8	uM	10002.034	0.1169	-0.9174	0.6736
184B5	NM	Basal	CPT-11	TOP1	TOP	0.000218	uM	9095.121	1.0088	1.0146	1.1992
184B5	NM	Basal	CPT-11	TOP1	TOP	0.00109	uM	9095.121	1.0845	1.1400	1.1992

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)