Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM102PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 20 | uM | 9777.049 | 0.7973 | 0.3922 | 0.6254 | |
| SUM102PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 100 | uM | 9777.049 | 0.9443 | 0.8248 | 0.6254 | |
| SUM102PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 500 | uM | 9777.049 | 1.1826 | 1.6149 | 0.6254 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9797.017 | 1.0081 | 1.0335 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9797.017 | 0.9727 | 0.8886 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9797.017 | 1.0123 | 1.0514 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9797.017 | 1.0359 | 1.1517 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9797.017 | 0.8915 | 0.5763 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9797.017 | 0.7772 | 0.1859 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9797.017 | 0.1895 | -0.9364 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9797.017 | 0.0182 | -0.9995 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9797.017 | 0.0028 | -1.0000 | 0.4824 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10139.021 | 1.0401 | 1.0960 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10139.021 | 0.9724 | 0.9343 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10139.021 | 1.0296 | 1.0708 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10139.021 | 1.0008 | 1.0019 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10139.021 | 0.9808 | 0.9543 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10139.021 | 0.8577 | 0.6656 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10139.021 | 0.1510 | -0.7899 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10139.021 | 0.0847 | -0.8946 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10139.021 | 0.0135 | -0.9882 | 0.8389 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7917.13 | 1.0749 | 1.0529 | 2.7649 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7917.13 | 0.9877 | 0.9911 | 2.7649 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7917.13 | 0.9934 | 0.9952 | 2.7649 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7917.13 | 0.9650 | 0.9744 | 2.7649 |