Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12684.174 | 0.9918 | 0.9887 | 1.4645 | |
| 184A1 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12684.174 | 0.9804 | 0.9731 | 1.4645 | |
| 184A1 | NM | Basal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12684.174 | 0.8809 | 0.8341 | 1.4645 | |
| 184A1 | NM | Basal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12684.174 | 0.6732 | 0.5264 | 1.4645 | |
| 184A1 | NM | Basal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12684.174 | 0.4726 | 0.1987 | 1.4645 | |
| 184B5 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12979.174 | 0.9483 | 0.9334 | 1.5680 | |
| 184B5 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12979.174 | 1.0998 | 1.1251 | 1.5680 | |
| 184B5 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12979.174 | 1.0345 | 1.0438 | 1.5680 | |
| 184B5 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12979.174 | 1.0010 | 1.0013 | 1.5680 | |
| 184B5 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12979.174 | 1.0302 | 1.0383 | 1.5680 | |
| 184B5 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12979.174 | 0.8458 | 0.7974 | 1.5680 | |
| 184B5 | NM | Basal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12979.174 | 0.9018 | 0.8724 | 1.5680 | |
| 184B5 | NM | Basal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12979.174 | 0.6483 | 0.5171 | 1.5680 | |
| 184B5 | NM | Basal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12979.174 | 0.0022 | -0.9600 | 1.5680 | |
| 21MT-1 | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13719.174 | 0.9822 | 0.9563 | 0.8124 | |
| 21MT-1 | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13719.174 | 0.9680 | 0.9215 | 0.8124 | |
| 21MT-1 | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13719.174 | 1.0095 | 1.0234 | 0.8124 | |
| 21MT-1 | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13719.174 | 0.9913 | 0.9786 | 0.8124 | |
| 21MT-1 | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13719.174 | 0.9397 | 0.8526 | 0.8124 | |
| 21MT-1 | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13719.174 | 0.9376 | 0.8474 | 0.8124 | |
| 21MT-1 | HER2amp | - | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13719.174 | 0.9520 | 0.8825 | 0.8124 | |
| 21MT-1 | HER2amp | - | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13719.174 | 0.9602 | 0.9025 | 0.8124 | |
| 21MT-1 | HER2amp | - | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13719.174 | 0.9443 | 0.8637 | 0.8124 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13575.174 | 0.9544 | 0.9419 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13575.174 | 0.9703 | 0.9624 | 1.5845 |