Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13078.176 | 0.9488 | 0.8589 | 0.7179 | |
| UACC-812 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13078.176 | 1.0011 | 1.0030 | 0.7179 | |
| UACC-812 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13078.176 | 0.9658 | 0.9053 | 0.7179 | |
| ZR-75-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12677.176 | 0.9567 | 0.9079 | 0.9376 | |
| ZR-75-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12677.176 | 0.9624 | 0.9199 | 0.9376 | |
| ZR-75-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12677.176 | 0.9678 | 0.9314 | 0.9376 | |
| ZR-75-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12677.176 | 0.9773 | 0.9517 | 0.9376 | |
| ZR-75-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12677.176 | 0.9845 | 0.9669 | 0.9376 | |
| ZR-75-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12677.176 | 0.9582 | 0.9110 | 0.9376 | |
| ZR-75-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12677.176 | 0.9675 | 0.9307 | 0.9376 | |
| ZR-75-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12677.176 | 0.9478 | 0.8888 | 0.9376 | |
| ZR-75-1 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12677.176 | 0.8920 | 0.7705 | 0.9376 | |
| ZR75B | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13595.176 | 0.9409 | 0.9374 | 1.9155 | |
| ZR75B | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13595.176 | 0.9652 | 0.9634 | 1.9155 | |
| ZR75B | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13595.176 | 0.9913 | 0.9909 | 1.9155 | |
| ZR75B | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13595.176 | 1.0034 | 1.0035 | 1.9155 | |
| ZR75B | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13595.176 | 0.9442 | 0.9410 | 1.9155 | |
| ZR75B | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13595.176 | 0.9560 | 0.9535 | 1.9155 | |
| ZR75B | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13595.176 | 0.9608 | 0.9586 | 1.9155 | |
| ZR75B | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13595.176 | 0.9754 | 0.9741 | 1.9155 | |
| ZR75B | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13595.176 | 0.8665 | 0.8559 | 1.9155 | |
| 184A1 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12684.174 | 0.9923 | 0.9894 | 1.4645 | |
| 184A1 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12684.174 | 1.0300 | 1.0408 | 1.4645 | |
| 184A1 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12684.174 | 1.0813 | 1.1097 | 1.4645 | |
| 184A1 | NM | Basal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12684.174 | 1.0431 | 1.0584 | 1.4645 |