Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12944.174 | 0.9644 | 0.9742 | 2.7985 | |
| MCF 10A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12944.174 | 1.0048 | 1.0034 | 2.7985 | |
| MCF 10A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12944.174 | 0.9363 | 0.9535 | 2.7985 | |
| MCF 10A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12944.174 | 0.4060 | 0.4492 | 2.7985 | |
| MCF 10A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12944.174 | 0.8034 | 0.8495 | 2.7985 | |
| MCF 10A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12944.174 | 0.7282 | 0.7857 | 2.7985 | |
| MCF 10A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12944.174 | 0.9815 | 0.9867 | 2.7985 | |
| MCF 10F | NM | - | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13750.174 | 0.9445 | 0.9217 | 1.4282 | |
| MCF 10F | NM | - | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13750.174 | 0.9272 | 0.8969 | 1.4282 | |
| MCF 10F | NM | - | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13750.174 | 0.9799 | 0.9718 | 1.4282 | |
| MCF 10F | NM | - | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13750.174 | 0.9693 | 0.9568 | 1.4282 | |
| MCF 10F | NM | - | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13750.174 | 0.9686 | 0.9558 | 1.4282 | |
| MCF 10F | NM | - | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13750.174 | 0.7931 | 0.7003 | 1.4282 | |
| MCF 10F | NM | - | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13750.174 | 0.9257 | 0.8947 | 1.4282 | |
| MCF 10F | NM | - | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13750.174 | 0.8320 | 0.7584 | 1.4282 | |
| MCF 10F | NM | - | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13750.174 | 0.8117 | 0.7281 | 1.4282 | |
| MCF12A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12949.174 | 0.9358 | 0.9314 | 1.9016 | |
| MCF12A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12949.174 | 0.9995 | 0.9995 | 1.9016 | |
| MCF12A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12949.174 | 0.9190 | 0.9131 | 1.9016 | |
| MCF12A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12949.174 | 0.9729 | 0.9713 | 1.9016 | |
| MCF12A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12949.174 | 0.8614 | 0.8491 | 1.9016 | |
| MCF12A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12949.174 | 0.5779 | 0.4990 | 1.9016 | |
| MCF12A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12949.174 | 0.8785 | 0.8683 | 1.9016 | |
| MCF12A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12949.174 | 0.6864 | 0.6409 | 1.9016 | |
| MCF12A | NM | Basal B | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12949.174 | 0.4263 | 0.2773 | 1.9016 |