Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 9469.037 | 0.2478 | -0.4596 | 1.0663 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 9469.037 | 0.1575 | -0.6467 | 1.0663 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7856.05 | 1.0263 | 1.0719 | 0.7346 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7856.05 | 1.0894 | 1.2473 | 0.7346 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7856.05 | 1.0465 | 1.1276 | 0.7346 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7856.05 | 1.0800 | 1.2209 | 0.7346 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7856.05 | 0.7938 | 0.4604 | 0.7346 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7856.05 | 0.3852 | -0.4541 | 0.7346 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7856.05 | 0.2668 | -0.6690 | 0.7346 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7856.05 | 0.2804 | -0.6457 | 0.7346 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7856.05 | 0.1316 | -0.8736 | 0.7346 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7857.037 | 1.0170 | 1.0293 | 1.1628 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7857.037 | 1.0694 | 1.1188 | 1.1628 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7857.037 | 0.9851 | 0.9744 | 1.1628 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7857.037 | 1.1200 | 1.2048 | 1.1628 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7857.037 | 0.9380 | 0.8930 | 1.1628 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7857.037 | 0.5148 | 0.1299 | 1.1628 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7857.037 | 0.3223 | -0.2447 | 1.1628 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7857.037 | 0.2709 | -0.3496 | 1.1628 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7857.037 | 0.2129 | -0.4713 | 1.1628 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7857.05 | 0.9704 | 0.9525 | 1.2527 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7857.05 | 1.0267 | 1.0426 | 1.2527 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7857.05 | 1.0083 | 1.0132 | 1.2527 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7857.05 | 1.0421 | 1.0669 | 1.2527 | |
| HCC70 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7857.05 | 0.7309 | 0.5572 | 1.2527 |