Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9028.05 | 1.1053 | 1.2274 | 0.9299 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9028.05 | 1.0691 | 1.1491 | 0.9299 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9028.05 | 1.1075 | 1.2321 | 0.9299 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9028.05 | 0.7770 | 0.5247 | 0.9299 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9028.05 | 0.4732 | -0.1054 | 0.9299 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9028.05 | 0.3621 | -0.3291 | 0.9299 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 9028.05 | 0.3207 | -0.4112 | 0.9299 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 9028.05 | 0.2710 | -0.5088 | 0.9299 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 9028.05 | 0.2588 | -0.5325 | 0.9299 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9453.037 | 0.9923 | 0.9871 | 1.1917 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9453.037 | 1.0025 | 1.0042 | 1.1917 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9453.037 | 1.0429 | 1.0718 | 1.1917 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9453.037 | 0.8873 | 0.8090 | 1.1917 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9453.037 | 0.4192 | -0.0358 | 1.1917 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9453.037 | 0.3151 | -0.2412 | 1.1917 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 9453.037 | 0.2442 | -0.3873 | 1.1917 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 9453.037 | 0.1726 | -0.5422 | 1.1917 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 9453.037 | 0.0779 | -0.7652 | 1.1917 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9469.037 | 1.0668 | 1.1251 | 1.0663 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9469.037 | 1.0173 | 1.0324 | 1.0663 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9469.037 | 1.0701 | 1.1313 | 1.0663 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9469.037 | 0.9886 | 0.9786 | 1.0663 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9469.037 | 0.5526 | 0.1467 | 1.0663 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9469.037 | 0.3683 | -0.2161 | 1.0663 | |
| HCC38 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 9469.037 | 0.3316 | -0.2897 | 1.0663 |