Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9278.037 | 1.0262 | 1.1398 | 0.3822 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9278.037 | 1.0564 | 1.3085 | 0.3822 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9278.037 | 0.9983 | 0.9912 | 0.3822 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9278.037 | 0.8171 | 0.1789 | 0.3822 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9278.037 | 0.2654 | -0.9378 | 0.3822 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9278.037 | 0.2441 | -0.9501 | 0.3822 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9278.037 | 0.2236 | -0.9603 | 0.3822 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9278.037 | 0.1387 | -0.9886 | 0.3822 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9278.037 | 0.0486 | -0.9993 | 0.3822 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 10019.037 | 1.1132 | 1.5767 | 0.4232 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 10019.037 | 1.0353 | 1.1711 | 0.4232 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 10019.037 | 1.0457 | 1.2228 | 0.4232 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 10019.037 | 1.0215 | 1.1030 | 0.4232 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 10019.037 | 0.4548 | -0.6892 | 0.4232 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 10019.037 | 0.3797 | -0.7970 | 0.4232 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 10019.037 | 0.3271 | -0.8574 | 0.4232 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 10019.037 | 0.2248 | -0.9412 | 0.4232 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 10019.037 | 0.0463 | -0.9986 | 0.4232 | |
| HCC1428 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9294.037 | 1.0441 | 1.1102 | 0.8050 | |
| HCC1428 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9294.037 | 0.9958 | 0.9896 | 0.8050 | |
| HCC1428 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9294.037 | 0.9822 | 0.9558 | 0.8050 | |
| HCC1428 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9294.037 | 0.5906 | 0.0396 | 0.8050 | |
| HCC1428 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9294.037 | 0.4774 | -0.2018 | 0.8050 | |
| HCC1428 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9294.037 | 0.4861 | -0.1837 | 0.8050 | |
| HCC1428 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9294.037 | 0.4943 | -0.1666 | 0.8050 |