Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7820.04 | 1.0604 | 1.1654 | 0.7382 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7820.04 | 0.9269 | 0.8047 | 0.7382 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7820.04 | 0.7278 | 0.3006 | 0.7382 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7820.04 | 0.3680 | -0.4837 | 0.7382 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7820.04 | 0.3382 | -0.5394 | 0.7382 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7820.04 | 0.2478 | -0.6978 | 0.7382 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7820.04 | 0.1879 | -0.7923 | 0.7382 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7820.05 | 0.9598 | 0.8148 | 0.4219 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7820.05 | 1.0216 | 1.1038 | 0.4219 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7820.05 | 0.9485 | 0.7643 | 0.4219 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7820.05 | 1.0059 | 1.0283 | 0.4219 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7820.05 | 0.5649 | -0.4834 | 0.4219 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7820.05 | 0.4170 | -0.7484 | 0.4219 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7820.05 | 0.3933 | -0.7811 | 0.4219 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7820.05 | 0.2734 | -0.9075 | 0.4219 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7820.05 | 0.0648 | -0.9970 | 0.4219 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7821.05 | 0.9746 | 0.8407 | 0.3098 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7821.05 | 1.0116 | 1.0759 | 0.3098 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7821.05 | 0.9939 | 0.9612 | 0.3098 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7821.05 | 0.9710 | 0.8190 | 0.3098 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7821.05 | 0.4979 | -0.7893 | 0.3098 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7821.05 | 0.4280 | -0.8707 | 0.3098 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7821.05 | 0.4116 | -0.8860 | 0.3098 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7821.05 | 0.3007 | -0.9586 | 0.3098 | |
| HCC1419 | HER2amp | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7821.05 | 0.0395 | -0.9999 | 0.3098 |