Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9047.037 | 0.4280 | -0.6013 | 0.5262 | |
| 184A1 | NM | Basal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9047.037 | 0.4311 | -0.5959 | 0.5262 | |
| 184A1 | NM | Basal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9047.037 | 0.4226 | -0.6108 | 0.5262 | |
| 184A1 | NM | Basal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9047.037 | 0.3683 | -0.7003 | 0.5262 | |
| 184A1 | NM | Basal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9047.037 | 0.0825 | -0.9826 | 0.5262 | |
| 184B5 | NM | Basal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9095.037 | 1.0187 | 1.0373 | 1.0013 | |
| 184B5 | NM | Basal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9095.037 | 1.0407 | 1.0812 | 1.0013 | |
| 184B5 | NM | Basal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9095.037 | 1.0285 | 1.0568 | 1.0013 | |
| 184B5 | NM | Basal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9095.037 | 0.4901 | -0.0190 | 1.0013 | |
| 184B5 | NM | Basal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9095.037 | 0.1746 | -0.6499 | 1.0013 | |
| 184B5 | NM | Basal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9095.037 | 0.1564 | -0.6864 | 1.0013 | |
| 184B5 | NM | Basal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9095.037 | 0.1154 | -0.7686 | 1.0013 | |
| 184B5 | NM | Basal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9095.037 | 0.1104 | -0.7785 | 1.0013 | |
| 184B5 | NM | Basal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9095.037 | 0.0306 | -0.9385 | 1.0013 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7791.05 | 0.9836 | 0.9588 | 0.7929 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7791.05 | 1.0197 | 1.0499 | 0.7929 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7791.05 | 0.9733 | 0.9329 | 0.7929 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7791.05 | 0.9305 | 0.8264 | 0.7929 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7791.05 | 0.6554 | 0.1738 | 0.7929 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7791.05 | 0.6611 | 0.1867 | 0.7929 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7791.05 | 0.6195 | 0.0933 | 0.7929 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7791.05 | 0.6470 | 0.1548 | 0.7929 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7791.05 | 0.2634 | -0.6281 | 0.7929 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9118.037 | 0.9526 | 0.9116 | 1.0733 | |
| 600MPE | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9118.037 | 0.9938 | 0.9885 | 1.0733 |