Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9708.019 | 0.9489 | 0.9114 | 1.1580 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9708.019 | 0.8642 | 0.7632 | 1.1580 | ||
| MDA-MB-453 | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9708.019 | 0.2755 | -0.3430 | 1.1580 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7905.016 | 1.2238 | 1.7643 | 0.6240 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7905.016 | 0.7257 | 0.1965 | 0.6240 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7905.016 | 1.1139 | 1.3776 | 0.6240 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7905.016 | 0.9434 | 0.8217 | 0.6240 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7905.016 | 1.1695 | 1.5704 | 0.6240 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7905.016 | 0.6847 | 0.0899 | 0.6240 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7905.016 | 0.7233 | 0.1901 | 0.6240 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7905.016 | 0.6497 | 0.0019 | 0.6240 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7905.016 | 0.1274 | -0.9264 | 0.6240 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7906.016 | 0.7239 | 0.3372 | 0.8028 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7906.016 | 0.7847 | 0.4786 | 0.8028 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7906.016 | 0.9549 | 0.8882 | 0.8028 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7906.016 | 0.7337 | 0.3598 | 0.8028 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7906.016 | 0.9726 | 0.9319 | 0.8028 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7906.016 | 0.5562 | -0.0370 | 0.8028 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7906.016 | 0.6407 | 0.1487 | 0.8028 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7906.016 | 0.8779 | 0.7004 | 0.8028 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7906.016 | 0.2496 | -0.6451 | 0.8028 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7907.016 | 1.1648 | 1.2461 | 1.3145 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7907.016 | 0.8839 | 0.8207 | 1.3145 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7907.016 | 1.1776 | 1.2649 | 1.3145 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7907.016 | 0.9249 | 0.8847 | 1.3145 |