Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7879.017 | 0.4389 | 0.2578 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7879.017 | 0.3043 | 0.0233 | 1.7754 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7885.017 | 1.0008 | 1.0028 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7885.017 | 1.0506 | 1.1829 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7885.017 | 0.9957 | 0.9849 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7885.017 | 0.9829 | 0.9399 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7885.017 | 0.8557 | 0.5175 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7885.017 | 0.7974 | 0.3394 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7885.017 | 0.5421 | -0.3239 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7885.017 | 0.2317 | -0.8499 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7885.017 | 0.1144 | -0.9570 | 0.5647 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7886.017 | 1.0404 | 1.1127 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7886.017 | 0.9929 | 0.9804 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7886.017 | 0.9969 | 0.9915 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7886.017 | 1.0038 | 1.0104 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7886.017 | 0.8838 | 0.6859 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7886.017 | 0.8188 | 0.5168 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7886.017 | 0.5226 | -0.1849 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7886.017 | 0.2057 | -0.7756 | 0.7230 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7886.017 | 0.1170 | -0.8971 | 0.7230 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7892.017 | 1.0242 | 1.0196 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7892.017 | 1.0459 | 1.0370 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7892.017 | 0.9981 | 0.9984 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7892.017 | 0.9500 | 0.9585 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7892.017 | 0.7270 | 0.7559 | 2.4495 |