Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7892.017 | 0.5683 | 0.5879 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7892.017 | 0.4362 | 0.4254 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7892.017 | 0.2652 | 0.1633 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7892.017 | 0.1462 | -0.0878 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7893.017 | 0.9781 | 0.9808 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7893.017 | 0.9667 | 0.9706 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7893.017 | 1.0411 | 1.0355 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7893.017 | 0.9551 | 0.9603 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7893.017 | 0.7944 | 0.8087 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7893.017 | 0.6289 | 0.6333 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7893.017 | 0.4596 | 0.4242 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7893.017 | 0.2840 | 0.1543 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7893.017 | 0.1566 | -0.1099 | 2.2898 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7896.017 | 1.0328 | 1.0649 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7896.017 | 1.0005 | 1.0010 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7896.017 | 1.0458 | 1.0906 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7896.017 | 0.9174 | 0.8365 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7896.017 | 0.8587 | 0.7202 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7896.017 | 0.7874 | 0.5790 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7896.017 | 0.4540 | -0.0841 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7896.017 | 0.1843 | -0.6243 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7896.017 | 0.0617 | -0.8727 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9648.017 | 1.0496 | 1.1762 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9648.017 | 1.0079 | 1.0275 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9648.017 | 1.0192 | 1.0675 | 0.5727 |