Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7853.017 | 0.3388 | 0.0727 | 1.7375 | |
| HCC3153 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7853.017 | 0.2696 | -0.0594 | 1.7375 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7854.017 | 0.8300 | 0.7349 | 1.3102 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7854.017 | 1.0402 | 1.0611 | 1.3102 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7854.017 | 0.8074 | 0.6987 | 1.3102 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7854.017 | 0.9322 | 0.8957 | 1.3102 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7854.017 | 0.7804 | 0.6552 | 1.3102 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7854.017 | 0.6656 | 0.4658 | 1.3102 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7854.017 | 0.4904 | 0.1611 | 1.3102 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7854.017 | 0.3018 | -0.1986 | 1.3102 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7854.017 | 0.1570 | -0.5133 | 1.3102 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 9453.017 | 1.0298 | 1.0484 | 1.2279 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 9453.017 | 1.0241 | 1.0392 | 1.2279 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 9453.017 | 1.0291 | 1.0473 | 1.2279 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 9453.017 | 1.0448 | 1.0727 | 1.2279 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 9453.017 | 0.8252 | 0.7104 | 1.2279 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 9453.017 | 0.7222 | 0.5343 | 1.2279 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 9453.017 | 0.5396 | 0.2101 | 1.2279 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 9453.017 | 0.2851 | -0.2803 | 1.2279 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 9453.017 | 0.1687 | -0.5306 | 1.2279 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 9469.131 | 1.0533 | 1.1002 | 1.0627 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 9469.131 | 0.9781 | 0.9587 | 1.0627 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 9469.131 | 1.0719 | 1.1351 | 1.0627 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 9469.131 | 1.0898 | 1.1686 | 1.0627 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 9469.131 | 1.0063 | 1.0118 | 1.0627 |