Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 9469.131 | 0.8634 | 0.7417 | 1.0627 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 9469.131 | 0.6898 | 0.4101 | 1.0627 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 9469.131 | 0.2937 | -0.3685 | 1.0627 | |
| HCC38 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 9469.131 | 0.1796 | -0.6025 | 1.0627 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7857.017 | 0.9972 | 0.9953 | 1.1840 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7857.017 | 0.9451 | 0.9068 | 1.1840 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7857.017 | 0.8192 | 0.6899 | 1.1840 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7857.017 | 0.8211 | 0.6932 | 1.1840 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7857.017 | 0.8038 | 0.6631 | 1.1840 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7857.017 | 0.5882 | 0.2776 | 1.1840 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7857.017 | 0.0746 | -0.7766 | 1.1840 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7857.017 | 0.0125 | -0.9505 | 1.1840 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7857.017 | 0.0085 | -0.9642 | 1.1840 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7860.017 | 1.0064 | 1.0206 | 0.6196 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7860.017 | 0.9909 | 0.9706 | 0.6196 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7860.017 | 1.0014 | 1.0046 | 0.6196 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7860.017 | 0.9291 | 0.7763 | 0.6196 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7860.017 | 0.9830 | 0.9455 | 0.6196 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7860.017 | 0.5060 | -0.3338 | 0.6196 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7860.017 | 0.1227 | -0.9323 | 0.6196 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7860.017 | 0.0222 | -0.9957 | 0.6196 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7860.017 | 0.0101 | -0.9988 | 0.6196 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 9501.03 | 1.0856 | 1.2528 | 0.6902 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 9501.03 | 1.0644 | 1.1893 | 0.6902 | |
| HCC70 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 9501.03 | 1.0873 | 1.2579 | 0.6902 |