Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 7830.018 | 0.0500 | -0.7172 | 1.5320 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 7830.018 | 0.0064 | -0.9259 | 1.5320 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9376.026 | 1.0805 | 1.0942 | 1.6827 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 9376.026 | 1.0780 | 1.0913 | 1.6827 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 9376.026 | 0.9773 | 0.9729 | 1.6827 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 9376.026 | 0.6111 | 0.4926 | 1.6827 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 9376.026 | 0.6370 | 0.5298 | 1.6827 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 9376.026 | 0.6623 | 0.5657 | 1.6827 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 9376.026 | 0.5901 | 0.4618 | 1.6827 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 9376.026 | 0.0583 | -0.6305 | 1.6827 | ||
| HCC1806 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 9376.026 | 0.0064 | -0.9007 | 1.6827 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7834.018 | 1.0051 | 1.0054 | 1.8951 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 7834.018 | 0.9674 | 0.9653 | 1.8951 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 7834.018 | 0.7432 | 0.7101 | 1.8951 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 7834.018 | 0.5721 | 0.4895 | 1.8951 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 7834.018 | 0.5953 | 0.5211 | 1.8951 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 7834.018 | 0.5347 | 0.4373 | 1.8951 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 7834.018 | 0.4480 | 0.3092 | 1.8951 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 7834.018 | 0.3217 | 0.0994 | 1.8951 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 7834.018 | 0.0878 | -0.4460 | 1.8951 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10262.034 | 0.9956 | 0.9869 | 0.6634 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 10262.034 | 0.9672 | 0.9021 | 0.6634 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 10262.034 | 0.8778 | 0.6432 | 0.6634 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 10262.034 | 0.7541 | 0.3070 | 0.6634 | ||
| HCC1937 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 10262.034 | 0.7437 | 0.2798 | 0.6634 |