Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9157.034 | 0.9558 | 0.9165 | 1.0593 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9157.034 | 0.9443 | 0.8947 | 1.0593 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9157.034 | 0.9621 | 0.9283 | 1.0593 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9157.034 | 0.8386 | 0.6937 | 1.0593 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9157.034 | 0.7964 | 0.6131 | 1.0593 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9157.034 | 0.8256 | 0.6689 | 1.0593 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9157.034 | 0.7499 | 0.5242 | 1.0593 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9157.034 | 0.5309 | 0.1002 | 1.0593 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9157.034 | 0.0139 | -0.9646 | 1.0593 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.000256 | uM | 9158.123 | 0.9743 | 0.9414 | 0.8769 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.00128 | uM | 9158.123 | 0.9163 | 0.8103 | 0.8769 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0064 | uM | 9158.123 | 0.9641 | 0.9183 | 0.8769 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.032 | uM | 9158.123 | 0.9264 | 0.8330 | 0.8769 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.16 | uM | 9158.123 | 0.9383 | 0.8599 | 0.8769 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.8 | uM | 9158.123 | 0.8949 | 0.7620 | 0.8769 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 4 | uM | 9158.123 | 0.7564 | 0.4547 | 0.8769 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 20 | uM | 9158.123 | 0.3174 | -0.4596 | 0.8769 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 100 | uM | 9158.123 | 0.0064 | -0.9937 | 0.8769 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9163.026 | 0.9770 | 0.8795 | 0.3738 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9163.026 | 0.9951 | 0.9739 | 0.3738 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9163.026 | 0.9555 | 0.7708 | 0.3738 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9163.026 | 0.8262 | 0.2002 | 0.3738 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9163.026 | 0.7780 | 0.0217 | 0.3738 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9163.026 | 0.7582 | -0.0461 | 0.3738 | ||
| BT-474 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9163.026 | 0.7617 | -0.0344 | 0.3738 |