Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7818.018 | 0.7965 | 0.5905 | 0.9928 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7818.018 | 0.7572 | 0.5113 | 0.9928 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7818.018 | 0.7317 | 0.4600 | 0.9928 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7818.018 | 0.4479 | -0.1094 | 0.9928 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7818.018 | 0.0394 | -0.9231 | 0.9928 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9278.026 | 1.0206 | 1.1239 | 0.3395 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9278.026 | 0.9530 | 0.7357 | 0.3395 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9278.026 | 0.9586 | 0.7657 | 0.3395 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9278.026 | 0.8483 | 0.2318 | 0.3395 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9278.026 | 0.8170 | 0.1027 | 0.3395 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9278.026 | 0.7512 | -0.1387 | 0.3395 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9278.026 | 0.7457 | -0.1574 | 0.3395 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9278.026 | 0.4311 | -0.8322 | 0.3395 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9278.026 | 0.0137 | -1.0000 | 0.3395 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.00128 | uM | 10019.124 | 1.0352 | 1.1334 | 0.5356 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0064 | uM | 10019.124 | 1.0546 | 1.2086 | 0.5356 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.032 | uM | 10019.124 | 1.0074 | 1.0278 | 0.5356 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.16 | uM | 10019.124 | 0.8930 | 0.6191 | 0.5356 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.8 | uM | 10019.124 | 0.8862 | 0.5961 | 0.5356 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 4 | uM | 10019.124 | 0.8722 | 0.5493 | 0.5356 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 20 | uM | 10019.124 | 0.8484 | 0.4712 | 0.5356 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 100 | uM | 10019.124 | 0.4683 | -0.5148 | 0.5356 | ||
| HCC1419 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 500 | uM | 10019.124 | 0.0427 | -0.9945 | 0.5356 | ||
| HCC1428 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9294.125 | 1.0375 | 1.1080 | 0.6999 | ||
| HCC1428 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9294.125 | 0.9623 | 0.8932 | 0.6999 |