Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | CGC-11047 | Polyamine analogue | 200 | uM | 9095.026 | 1.1856 | 1.3646 | 1.0168 | ||
| 184B5 | NM | Basal | CGC-11047 | Polyamine analogue | 1000 | uM | 9095.026 | 0.0874 | -0.8180 | 1.0168 | ||
| 184B5 | NM | Basal | CGC-11047 | Polyamine analogue | 5000 | uM | 9095.026 | 0.0205 | -0.9562 | 1.0168 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7791.018 | 1.1251 | 1.2954 | 0.8558 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7791.018 | 0.9672 | 0.9235 | 0.8558 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7791.018 | 1.0039 | 1.0091 | 0.8558 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7791.018 | 0.8052 | 0.5526 | 0.8558 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7791.018 | 0.7952 | 0.5302 | 0.8558 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7791.018 | 0.7458 | 0.4198 | 0.8558 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7791.018 | 0.7795 | 0.4950 | 0.8558 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7791.018 | 0.6835 | 0.2821 | 0.8558 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7791.018 | 0.2878 | -0.5335 | 0.8558 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9118.006 | 1.0125 | 1.0225 | 1.1089 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9118.006 | 0.9987 | 0.9977 | 1.1089 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9118.006 | 0.8011 | 0.6375 | 1.1089 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9118.006 | 0.7061 | 0.4613 | 1.1089 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9118.006 | 0.7372 | 0.5193 | 1.1089 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9118.006 | 0.7265 | 0.4993 | 1.1089 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9118.006 | 0.6806 | 0.4137 | 1.1089 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9118.006 | 0.6189 | 0.2975 | 1.1089 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9118.006 | 0.2884 | -0.3482 | 1.1089 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9120.034 | 1.0353 | 1.1194 | 0.5982 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9120.034 | 0.9993 | 0.9977 | 0.5982 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9120.034 | 1.0735 | 1.2518 | 0.5982 | ||
| 600MPE | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9120.034 | 0.8886 | 0.6415 | 0.5982 |