Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9210.026 | 0.9063 | 0.7952 | 0.9102 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9210.026 | 0.8725 | 0.7216 | 0.9102 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9210.026 | 0.8778 | 0.7331 | 0.9102 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9210.026 | 0.8947 | 0.7698 | 0.9102 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9210.026 | 0.8760 | 0.7292 | 0.9102 | ||
| CAMA-1 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9210.026 | 0.0546 | -0.9180 | 0.9102 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.00128 | uM | 7808.052 | 1.0532 | 1.0422 | 2.4842 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.0064 | uM | 7808.052 | 0.9430 | 0.9533 | 2.4842 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.032 | uM | 7808.052 | 1.0211 | 1.0169 | 2.4842 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.16 | uM | 7808.052 | 0.9207 | 0.9346 | 2.4842 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.8 | uM | 7808.052 | 0.7328 | 0.7647 | 2.4842 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 4 | uM | 7808.052 | 0.6961 | 0.7286 | 2.4842 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 20 | uM | 7808.052 | 0.6341 | 0.6649 | 2.4842 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 100 | uM | 7808.052 | 0.6223 | 0.6523 | 2.4842 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 500 | uM | 7808.052 | 0.5640 | 0.5882 | 2.4842 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9226.034 | 1.0097 | 1.0074 | 2.6175 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.064 | uM | 9226.034 | 0.9543 | 0.9646 | 2.6175 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.32 | uM | 9226.034 | 0.9190 | 0.9365 | 2.6175 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 1.6 | uM | 9226.034 | 0.7418 | 0.7843 | 2.6175 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 8 | uM | 9226.034 | 0.7251 | 0.7689 | 2.6175 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 40 | uM | 9226.034 | 0.7574 | 0.7986 | 2.6175 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 200 | uM | 9226.034 | 0.7207 | 0.7647 | 2.6175 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 1000 | uM | 9226.034 | 0.6623 | 0.7087 | 2.6175 | ||
| HBL-100 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 5000 | uM | 9226.034 | 0.0282 | -0.4886 | 2.6175 | ||
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7809.018 | 1.0383 | 1.0454 | 1.6742 |