Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9033.018 | 1.0678 | 1.1565 | 0.8708 | |
| T47D | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9033.018 | 0.9752 | 0.9432 | 0.8708 | |
| T47D | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9033.018 | 1.0415 | 1.0955 | 0.8708 | |
| T47D | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9033.018 | 1.0220 | 1.0507 | 0.8708 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7926.018 | 0.9475 | 0.8999 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7926.018 | 1.0298 | 1.0567 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7926.018 | 0.9709 | 0.9446 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7926.018 | 1.0305 | 1.0580 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7926.018 | 1.0247 | 1.0471 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7926.018 | 1.0726 | 1.1381 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7926.018 | 0.9347 | 0.8754 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7926.018 | 1.0341 | 1.0650 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7926.018 | 1.0501 | 1.0954 | 1.0502 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 10267.026 | 1.0327 | 1.2168 | 0.3125 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 10267.026 | 1.3001 | 3.6322 | 0.3125 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 10267.026 | 1.0001 | 1.0004 | 0.3125 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 10267.026 | 1.1467 | 2.0990 | 0.3125 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 10267.026 | 1.1955 | 2.5416 | 0.3125 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 10267.026 | 1.2100 | 2.6814 | 0.3125 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 10267.026 | 1.0315 | 1.2089 | 0.3125 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 10267.026 | 1.0809 | 1.5657 | 0.3125 | |
| UACC-812 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 10267.026 | 1.1107 | 1.7985 | 0.3125 | |
| UACC-893 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9045.018 | 0.9847 | 0.9716 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9045.018 | 1.0992 | 1.1829 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9045.018 | 0.9662 | 0.9374 | 1.0807 |