Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7899.018 | 1.0614 | 1.0592 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7899.018 | 0.8545 | 0.8519 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7900.018 | 0.8940 | 0.7476 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7900.018 | 0.8675 | 0.6853 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7900.018 | 0.5716 | 0.0197 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7900.018 | 1.1625 | 1.3977 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7900.018 | 1.2547 | 1.6284 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7900.018 | 1.1996 | 1.4900 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7900.018 | 1.2596 | 1.6409 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7900.018 | 0.8176 | 0.5694 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7900.018 | 1.0761 | 1.1847 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7902.018 | 0.9595 | 0.9562 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7902.018 | 1.4257 | 1.4180 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7902.018 | 0.9133 | 0.9053 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7902.018 | 1.1141 | 1.1191 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7902.018 | 1.2141 | 1.2189 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7902.018 | 1.1001 | 1.1048 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7902.018 | 1.0368 | 1.0391 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7902.018 | 1.3382 | 1.3374 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7902.018 | 1.3479 | 1.3465 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 10266.026 | 0.9598 | 0.8807 | 0.6682 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 10266.026 | 1.2475 | 1.7845 | 0.6682 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 10266.026 | 0.9448 | 0.8372 | 0.6682 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 10266.026 | 1.0568 | 1.1724 | 0.6682 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 10266.026 | 1.1597 | 1.4964 | 0.6682 |