Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 10266.026 | 1.0687 | 1.2092 | 0.6682 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 10266.026 | 1.0587 | 1.1784 | 0.6682 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 10266.026 | 1.2356 | 1.7448 | 0.6682 | |
| MDA-MB-436 | TNBC | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 10266.026 | 0.9083 | 0.7319 | 0.6682 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7903.042 | 1.0325 | 1.0564 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7903.042 | 0.9683 | 0.9448 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7903.042 | 1.0136 | 1.0235 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7903.042 | 1.0533 | 1.0923 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7903.042 | 0.9556 | 0.9226 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7903.042 | 1.0123 | 1.0214 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7903.042 | 1.0221 | 1.0383 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7903.042 | 0.9975 | 0.9956 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7903.042 | 0.9978 | 0.9962 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9708.006 | 0.7177 | 0.1826 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9708.006 | 0.8031 | 0.4132 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9708.006 | 0.7665 | 0.3125 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9708.006 | 0.8327 | 0.4965 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9708.006 | 1.0588 | 1.1894 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9708.006 | 0.8755 | 0.6202 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9708.006 | 0.8314 | 0.4928 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9708.006 | 0.9424 | 0.8206 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9708.006 | 0.7955 | 0.3920 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9723.124 | 1.0292 | 1.0595 | 0.9827 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9723.124 | 1.0505 | 1.1028 | 0.9827 | |
| MDA-MB-453 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9723.124 | 1.0754 | 1.1535 | 0.9827 |