Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.137 | uM | 7487.102 | 0.8220 | 0.7590 | 1.5273 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.685 | uM | 7487.102 | 0.6832 | 0.5584 | 1.5273 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7871.018 | 1.0313 | 1.0521 | 1.1973 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7871.018 | 1.1057 | 1.1752 | 1.1973 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7871.018 | 1.0643 | 1.1069 | 1.1973 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7871.018 | 1.0424 | 1.0706 | 1.1973 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7871.018 | 1.0626 | 1.1041 | 1.1973 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7871.018 | 1.0941 | 1.1560 | 1.1973 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7871.018 | 1.1360 | 1.2247 | 1.1973 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.137 | uM | 7871.018 | 1.0776 | 1.1288 | 1.1973 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.685 | uM | 7871.018 | 0.9411 | 0.9011 | 1.1973 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7872.042 | 1.0517 | 1.0753 | 1.3632 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7872.042 | 0.9307 | 0.8973 | 1.3632 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7872.042 | 0.9752 | 0.9635 | 1.3632 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7872.042 | 0.9943 | 0.9917 | 1.3632 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7872.042 | 0.9453 | 0.9192 | 1.3632 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7872.042 | 1.0243 | 1.0355 | 1.3632 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7872.042 | 1.1231 | 1.1778 | 1.3632 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.137 | uM | 7872.042 | 1.1453 | 1.2093 | 1.3632 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.685 | uM | 7872.042 | 1.1114 | 1.1611 | 1.3632 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9566.026 | 1.3818 | 1.3268 | 2.1367 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9566.026 | 1.0503 | 1.0465 | 2.1367 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9566.026 | 1.2642 | 1.2319 | 2.1367 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9566.026 | 0.9829 | 0.9840 | 2.1367 | |
| MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9566.026 | 1.0698 | 1.0642 | 2.1367 |