Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7870.018 | 0.9949 | 0.9955 | 2.2478 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7870.018 | 1.0495 | 1.0434 | 2.2478 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7870.018 | 1.0048 | 1.0042 | 2.2478 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7870.018 | 1.0601 | 1.0526 | 2.2478 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7870.018 | 1.0639 | 1.0559 | 2.2478 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7870.018 | 1.0272 | 1.0240 | 2.2478 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7870.018 | 0.9274 | 0.9341 | 2.2478 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 7870.018 | 0.6851 | 0.6903 | 2.2478 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 7870.018 | 0.4863 | 0.4513 | 2.2478 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9551.026 | 1.0287 | 1.0214 | 2.6508 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9551.026 | 1.0725 | 1.0535 | 2.6508 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9551.026 | 1.0401 | 1.0299 | 2.6508 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9551.026 | 1.0237 | 1.0177 | 2.6508 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9551.026 | 1.0490 | 1.0364 | 2.6508 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9551.026 | 1.0415 | 1.0309 | 2.6508 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9551.026 | 1.0110 | 1.0083 | 2.6508 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.137 | uM | 9551.026 | 0.8484 | 0.8797 | 2.6508 | |
MCF 10A | NM | Basal B | Cetuximab | EGFR | ErbB | 0.685 | uM | 9551.026 | 0.6790 | 0.7282 | 2.6508 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7487.102 | 1.0115 | 1.0150 | 1.5273 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7487.102 | 1.0005 | 1.0006 | 1.5273 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7487.102 | 1.0018 | 1.0023 | 1.5273 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7487.102 | 0.9866 | 0.9825 | 1.5273 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7487.102 | 0.9654 | 0.9544 | 1.5273 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7487.102 | 0.9029 | 0.8706 | 1.5273 | |
MCF 10F | NM | - | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7487.102 | 0.9313 | 0.9089 | 1.5273 |